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Using two separate drugs to lose weight naturally can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err along the side of caution and allow FDA do its job and demand some study be done so the public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on their own medications. Researchers found out that participants investing in this drug for the year, lost excess weight within a month and have kept the weight off through the 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, which can make them far better and safer. Combo-pilling will be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that by right now there aren't long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise hypertension and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.